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Diagrams of Mechanisms of Pain Referral

Page 8 from "The Biology of Trigger Points: What they are, what they do, and when and why they occur".



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Trigger Points: Mechanisms of Pain Referral

Trigger Point Pain Referral is a result of the way the body is wired. The following mechanisms of trigger point pain referral have been observed and described (1):-


Axon Branching:
A single nerve cell has pain input from two different areas of the body, one from a trigger point, and the other from somewhere else (the pain referral zone). The single nerve cell has no way of "knowing" which incoming axon branch caused it to fire; as far as the nerve cell is concerned, the pain message that it passes up to the brain could have come from either area of the body. The brain therefore registers pain in all areas that input to that nerve.

Diagram right:
The arrows represent a pain signal arising from a trigger point.
Trigger Point Pain Referral - Diagram of Axon Branching

Convergence Projection:
A nerve cell in the spinal cord has input from two or more pain carrying neurons. It is stimulated to fire by an incoming pain nerve attached to a trigger point, but has no way of signalling to the brain which incoming pain nerve has caused it to fire. Thus the brain registers pain in all the regions that send pain messages via that nerve cell.

Diagram right:
The final nerve is firing in response to a pain signal from a nerve connected to a Trigger Point.
Trigger Point Pain Referral - Diagram of Convergence Projection

Convergence Facilitation:
Works like a transistor. The nerve attached to the trigger point excites a nerve cell in the spinal cord, thus lowering that nerve's stimulus threshold and making it more willing to pass a pain signal from the pain referral area up to the brain.

Diagram right:
The trigger point associated neuron does not carry a pain message. It does however amplify any pain signal from the pain referral area.
Trigger Point Pain Referral - Diagram of Convergence Facilitation

Activity of the Sympathetic Nervous System:
The brain is wired to carry a message from the trigger point to the sympathetic nervous system. The sympahthetic nervous system responds by releasing nerve excitatory chemicals in the referral zone. Pain, changes in blood flow and mucus membrane secretion result.

Diagram right:
The sympathetic nervous system responds to a trigger point pain signal by releasing nerve excitatory chemicals .
Trigger Point Pain Referral - Diagram of Convergence Facilitation






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Biology of trigger points: Mechanisms of Pain Referral
© Bruce Thomson, EasyVigour Project



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